Extent and Consistency Across Generations of Linkage Disequilibrium in Commercial Layer Chicken Breeding Populations

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Extent and consistency across generations of linkage disequilibrium in commercial layer chicken breeding populations.

Recent studies report a surprisingly high degree of marker-to-marker linkage disequilibrium (LD) in ruminant livestock populations. This has important implications for QTL mapping and marker-assisted selection. This study evaluated LD between microsatellite markers in a number of breeding populations of layer chickens using the standardized chi-square (chi(2')) measure. The results show appreci...

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The amount of linkage disequilibrium (LD) is an important source of information about historical events of recombination and allows inferences about genetic diversity and genomic regions that have undergone selection. Linkage disequilibrium is equally important in studying effective population size and rate of inbreeding particularly in extensively raised and wild animal populations where pedig...

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An increasing interest is being placed in the detection of genes, or genomic regions, that have been targeted by selection because identifying signatures of selection can lead to a better understanding of genotype-phenotype relationships. A common strategy for the detection of selection signatures is to compare samples from distinct populations and to search for genomic regions with outstanding...

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ژورنال

عنوان ژورنال: Genetics

سال: 2005

ISSN: 1943-2631

DOI: 10.1534/genetics.105.040782